Many research programs often slow or stall after generating a gene list. The course covers the bioinformatics concepts and tools available for annotating and determining functional enrichment of a gene list and analyzing networks. The workshop is focused on the principles and concepts required for analyzing and conducting pathway analysis on a gene list from any organism, although focus will be on human and model Eukaryotic organisms. Specifically, we will focus on 1) getting more information about a gene list, 2) finding out how a set of genes is connected, 3) discovering what's enriched in a gene list (and using it for hypothesis generation) and 4) extending or refining a gene list. An analysis flow chart will be developed throughout the course.
Students will be required to complete the Cytoscape tutorials:
Target and audience
This workshop is geared towards biologists working with Omics data (e.g. gene expression, protein expression, molecular interactions, large-scale genetic screens and other omics data) from human and model Eukaryotic organisms who are interested in interpreting large gene lists resulting from their experiments. Concepts will be applicable to omics data from non-eukaryotic organisms, but software and demonstrations will not cover them. Prerequisite: Your own laptop computer. Minimum requirements: 1024x768 screen resolution, 1.5GHz CPU, 1GB RAM, recent versions of Windows, Mac OS X or Linux (Most computers purchased in the past 3-4 years likely meet these requirements).
Registration and information
The course is organized by the BIMIB Group of the Department of Informatics, Systems and Communication, in collaboration with the Department of Biotechnology and Biosciences and the the PhD Program in Translational and Molecular Medicine (DIMET) of the Università degli Studi di Milano Bicocca.
Please register by sending and email to joint-doctoral-course +at+ bimib.disco.unimib.it; the same address can be used to request other inquiries. There is no fee for registering.
Organized by: BIMIB DISCo and BtBs (Faculty of Mathematical, Physical and Natural Sciences) and DIMET (Faculty of Medicine).
The course has been made possible by the Regione Lombardia ASTIL program, project RetroNet, grant n. 12-4-5148000-40; U.A 053.